Direct detection in clinical samples of multiple gene mutations causing resistance of Mycobacterium tuberculosis to isoniazid and rifampicin using fluorogenic probes | Zendy

Mateu Espasa | Zendy; Julian GonzálezMartin | Zendy; Fernando Alcaide | Zendy; Lina Marcela Aragón | Zendy; J. Lonca | Zendy; Joxe Mari Manterola | Zendy; Margarita Salvadó | Zendy; Griselda Tudó | Zendy; Pilar Orús | Zendy; Pere Coll | Zendy

Open Access

Direct detection in clinical samples of multiple gene mutations causing resistance of Mycobacterium tuberculosis to isoniazid and rifampicin using fluorogenic probes

Author(s) -

Mateu Espasa,

Julian GonzálezMartin,

Fernando Alcaide,

Lina Marcela Aragón,

J. Lonca,

Joxe Mari Manterola,

Margarita Salvadó,

Griselda Tudó,

Pilar Orús,

Pere Coll

Publication year - 2005

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dki132

Subject(s) - rifampicin , isoniazid , mycobacterium tuberculosis , microbiology and biotechnology , tuberculosis , virology , biology , gene , antibacterial agent , antibiotics , medicine , genetics , pathology

This study evaluates a method based on real-time PCR for direct detection in clinical samples of the common mutations responsible for isoniazid and rifampicin resistance of Mycobacterium tuberculosis.

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