Anti-proliferative synergy of lysophospholipid analogues and ketoconazole against Trypanosoma cruzi (Kinetoplastida: Trypanosomatidae): cellular and ultrastructural analysis
Author(s) -
Ricardo M. SantaRita,
Renée Lira,
Helene Santos Barbosa,
Julio A. Urbina,
Solange L. de Castro
Publication year - 2005
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dki087
Subject(s) - ketoconazole , amastigote , trypanosoma cruzi , biology , intracellular , miltefosine , kinetoplastida , antiparasitic agent , pharmacology , microbiology and biotechnology , leishmania , immunology , leishmaniasis , parasite hosting , visceral leishmaniasis , antifungal , protozoal disease , malaria , world wide web , computer science
Investigation of the antiproliferative synergy of the lysophospholipid analogues (LPAs) edelfosine, ilmofosine and miltefosine with the ergosterol biosynthesis inhibitor ketoconazole against Trypanosoma cruzi.
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