Comparative activity of quinolones (ciprofloxacin, levofloxacin, moxifloxacin and garenoxacin) against extracellular and intracellular infection by Listeria monocytogenes and Staphylococcus aureus in J774 macrophages | Zendy

Cristina Seral | Zendy; M. Barcia-Macay | Zendy; M. P. Mingeot-Leclercq | Zendy; Paul M. Tulkens | Zendy; Françoise Van Bambeke | Zendy

Open Access

Comparative activity of quinolones (ciprofloxacin, levofloxacin, moxifloxacin and garenoxacin) against extracellular and intracellular infection by Listeria monocytogenes and Staphylococcus aureus in J774 macrophages

Author(s) -

Cristina Seral,

M. Barcia-Macay,

M. P. Mingeot-Leclercq,

Paul M. Tulkens,

Françoise Van Bambeke

Publication year - 2005

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dki059

Subject(s) - extracellular , moxifloxacin , levofloxacin , listeria monocytogenes , microbiology and biotechnology , intracellular , staphylococcus aureus , ciprofloxacin , antibacterial agent , ofloxacin , chemistry , antibiotics , biology , bacteria , biochemistry , genetics

Quinolones accumulate in eukaryotic cells and show activity against a large array of intracellular organisms, but systematic studies aimed at examining their pharmacodynamic profile against intracellular bacteria are scarce. The present work aims at comparing intracellular-to-extracellular activities in this context.

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