Economic evaluation of voriconazole compared with conventional amphotericin B for the primary treatment of aspergillosis in immunocompromised patients
Author(s) -
Richard P. Wenzel,
A. Del Favero,
C C Kibbler,
Thomas R. Rogers,
Coleman Rotstein,
Josephine Mauskopf,
Stephen Morris,
Haran T. Schlamm,
Peter F. Troke,
A Marciniak
Publication year - 2005
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkh535
Subject(s) - voriconazole , medicine , aspergillosis , clinical trial , amphotericin b , randomized controlled trial , intensive care unit , surgery , intensive care medicine , emergency medicine , antifungal , dermatology , immunology
The objective of this study was to conduct an economic evaluation of voriconazole compared with conventional amphotericin B deoxycholate (CAB) using data from a recently reported randomized comparative trial in patients with various underlying immunosuppressive conditions. This trial demonstrated the superiority of voriconazole in terms of clinical response, survival and safety when used as primary therapy for invasive aspergillosis.
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