Plasma levels of zidovudine twice daily compared with three times daily in six HIV-1-infected children | Zendy

Alina S Bergshoeff | Zendy; Pieter L. A. Fraaij | Zendy; Corrien Verweij | Zendy; Annemarie M. C. van Rossum | Zendy; Gwenda Verweel | Zendy; Nico G. Hartwig | Zendy; Ronald de Groot | Zendy; David M. Burger | Zendy

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Plasma levels of zidovudine twice daily compared with three times daily in six HIV-1-infected children

Author(s) -

Alina S Bergshoeff,

Pieter L. A. Fraaij,

Corrien Verweij,

Annemarie M. C. van Rossum,

Gwenda Verweel,

Nico G. Hartwig,

Ronald de Groot,

David M. Burger

Publication year - 2004

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkh490

Subject(s) - zidovudine , medicine , human immunodeficiency virus (hiv) , sida , pediatrics , virology , viral disease

Zidovudine is often administered every 12 h in HIV-infected children, but so far no pharmacokinetic data are available for the administration of this agent every 12 h. We have evaluated the plasma pharmacokinetics of zidovudine administered every 8 h versus every 12 h in HIV-1-infected children.

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