Viridans streptococci in endocarditis and neutropenic sepsis: biofilm formation and effects of antibiotics | Zendy

Elisabeth Presterl | Zendy; Andrea Grisold | Zendy; Sonja Reichmann | Zendy; Alexander M. Hirschl | Zendy; A. Georgopoulos | Zendy; W. Graninger | Zendy

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Viridans streptococci in endocarditis and neutropenic sepsis: biofilm formation and effects of antibiotics

Author(s) -

Elisabeth Presterl,

Andrea Grisold,

Sonja Reichmann,

Alexander M. Hirschl,

A. Georgopoulos,

W. Graninger

Publication year - 2004

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkh479

Subject(s) - viridans streptococci , endocarditis , antibiotics , microbiology and biotechnology , sepsis , biofilm , neutropenia , medicine , streptococcus , immunology , biology , bacteria , chemotherapy , genetics

Viridans group streptococci (VGS) are a frequent cause of bacterial endocarditis or sepsis in patients with neutropenia. Endocarditis in particular, is associated with plaque formation on the endocardium and valve leaflets whereas VGS septicaemia in neutropenic patients is caused by the influx of oral flora bacteria through mucositic lesions. This study examined the in vitro potency for biofilm formation of clinical VGS bloodstream isolates, and the effects of antibiotics on these biofilms.

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