Silver nanoparticles and polymeric medical devices: a new approach to prevention of infection? | Zendy

Franck Furno | Zendy; Kelly S. Morley | Zendy; Ben Wong | Zendy; Barry L. Sharp | Zendy; Polly L. Arnold | Zendy; Steven M. Howdle | Zendy; Roger Bayston | Zendy; Paul D. Brown | Zendy; P. Winship | Zendy; Helen J. Reid | Zendy

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Silver nanoparticles and polymeric medical devices: a new approach to prevention of infection?

Author(s) -

Franck Furno,

Kelly S. Morley,

Ben Wong,

Barry L. Sharp,

Polly L. Arnold,

Steven M. Howdle,

Roger Bayston,

Paul D. Brown,

P. Winship,

Helen J. Reid

Publication year - 2004

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkh478

Subject(s) - silver nanoparticle , antimicrobial , materials science , polymer , silicone , biomaterial , coating , nanoparticle , nuclear chemistry , nanotechnology , chemistry , composite material , organic chemistry

Implantable devices are major risk factors for hospital-acquired infection. Biomaterials coated with silver oxide or silver alloy have all been used in attempts to reduce infection, in most cases with controversial or disappointing clinical results. We have developed a completely new approach using supercritical carbon dioxide to impregnate silicone with nanoparticulate silver metal. This study aimed to evaluate the impregnated polymer for antimicrobial activity.

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