Treatment of experimental osteomyelitis by liposomal antibiotics
Author(s) -
Ashraf A. Kadry,
Saleh A. AlSuwayeh,
Adel R. A. AbdAllah,
Mohsen A. Bayomi
Publication year - 2004
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkh465
Subject(s) - antibiotics , vancomycin , medicine , ciprofloxacin , osteomyelitis , liposome , nephrotoxicity , pharmacology , drug , surgery , staphylococcus aureus , microbiology and biotechnology , toxicity , chemistry , bacteria , biology , biochemistry , genetics
Traditional antibiotic therapy of staphylococcal osteomyelitis by a single drug or a drug combination is ineffective in producing complete sterilization of infected bones. The aim of this study was to develop a non-traditional delivery system of antibiotics for treatment of chronic experimental osteomyelitis.
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