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Bactericidal activity of amoxicillin against non-susceptible Streptococcus pneumoniae in an in vitro pharmacodynamic model simulating the concentrations obtained with the 2000/125 mg sustained-release co-amoxiclav formulation
Author(s) -
David Sevillano,
Almudena Calvo,
María-José Giménez,
Luís Alou,
Lorenzo Aguilar,
E Valero,
Antonio J. Carcas,
J. Prieto
Publication year - 2004
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkh463
Subject(s) - amoxicillin , streptococcus pneumoniae , pharmacodynamics , in vitro , microbiology and biotechnology , antibacterial agent , streptococcaceae , pharmacology , medicine , antibiotics , pharmacokinetics , chemistry , biology , biochemistry
To investigate the bactericidal activity against Streptococcus pneumoniae of simulated amoxicillin serum concentrations obtained in humans after 2000/125 mg sustained-release (SR) and 875/125 mg co-amoxiclav administered twice and three times a day, respectively.

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