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Cefepime and the inoculum effect in tests with Klebsiella pneumoniae producing plasmid-mediated AmpC-type β-lactamase
Author(s) -
CheolIn Kang,
Hyunjoo Pai,
SungHan Kim,
Hong Bin Kim,
Eui-Chong Kim,
Myoungdon Oh,
Kang Won Choe
Publication year - 2004
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkh462
Subject(s) - cefepime , klebsiella pneumoniae , microbiology and biotechnology , plasmid , klebsiella , biology , enterobacteriaceae , cephalosporin , antibiotics , antibiotic resistance , escherichia coli , imipenem , gene , genetics
In the past decade, a new problem in Klebsiella pneumoniae strains has emerged: plasmid-mediated AmpC enzymes. This study was conducted to investigate the activity of cefepime against clinical isolates by determining the activities of cefepime and three other parenteral beta-lactam agents in standard and high inoculum MIC tests.

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