Alternative dosing regimens of liposomal amphotericin B (AmBisome) effective in treating murine systemic candidiasis
Author(s) -
Jill AdlerMoore,
Jon Olson,
Richard T. Proffitt
Publication year - 2004
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkh460
Subject(s) - amphotericin b , dosing , medicine , pharmacology , systemic candidiasis , antifungal , dermatology , corpus albicans
This study was done to determine whether high dose AmBisome (4-20 mg/kg), given intermittently, could reduce the frequency of dosing needed to treat murine systemic candidiasis when compared with conventional daily treatment.
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