Is it safe to use carbapenems in patients with a history of allergy to penicillin? | Zendy

Manica Sodhi | Zendy; Sandra S. Axtell | Zendy; Joyce M. Callahan | Zendy; Raja Shekar | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Is it safe to use carbapenems in patients with a history of allergy to penicillin?

Author(s) -

Manica Sodhi,

Sandra S. Axtell,

Joyce M. Callahan,

Raja Shekar

Publication year - 2004

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkh454

Subject(s) - penicillin , penicillin allergy , medicine , antibiotics , allergy , cephalosporin , microbiology and biotechnology , intensive care medicine , biology , immunology

The purpose of this retrospective study was to ascertain the clinical safety of administering carbapenems, namely imipenem/cilastatin and meropenem, in patients with a history of penicillin allergy compared with administering carbapenems in patients with no reported penicillin allergy. Carbapenems are similar in chemical structure to the penicillins and therefore are associated with a risk for allergic cross-hypersensitivity. Carbapenems are commonly avoided in patients with a reported penicillin allergy on the basis of a potential cross-hypersensitivity with penicillin, however, very few studies have been conducted describing the incidence of cross-hypersensitivity between penicillin and carbapenems.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research