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Tissue and serum levofloxacin concentrations in diabetic foot infection patients
Author(s) -
K. Oberdorfer,
Stefanie Swoboda,
A. Hamann,
U Baertsch,
Klaus Kusterer,
BertJan H. van den Born,
Torsten HoppeTichy,
Heiko Geiss,
Heike von Baum
Publication year - 2004
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkh412
Subject(s) - levofloxacin , medicine , ofloxacin , diabetic foot , debridement (dental) , diabetes mellitus , surgery , gastroenterology , microbiology and biotechnology , antibiotics , ciprofloxacin , biology , endocrinology
Levofloxacin has a high bioavailability and a broad antibacterial spectrum which covers the common pathogens found in acute and chronic diabetic foot infections. The purpose of our study was to determine the serum and tissue concentrations of levofloxacin when administered orally in patients with infected diabetic foot ulcers and to compare these values with microbiological findings.

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