Lectin-functionalized poly (lactide-co-glycolide) nanoparticles as oral/aerosolized antitubercular drug carriers for treatment of tuberculosis | Zendy

Anjali Sharma | Zendy; Sadhna Sharma | Zendy; G. K. Khuller | Zendy

Open Access

Lectin-functionalized poly (lactide-co-glycolide) nanoparticles as oral/aerosolized antitubercular drug carriers for treatment of tuberculosis

Author(s) -

Anjali Sharma,

Sadhna Sharma,

G. K. Khuller

Publication year - 2004

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkh411

Subject(s) - pharmacology , isoniazid , bioavailability , aerosolization , pharmacokinetics , oral administration , clofazimine , chemistry , drug , drug carrier , pyrazinamide , bioadhesive , rifampicin , medicine , drug delivery , tuberculosis , antibiotics , immunology , biochemistry , pathology , inhalation , leprosy , organic chemistry , anatomy

This study was carried out to explore lectin-functionalized poly (lactide-co-glycolide) nanoparticles (PLG-NPs) as bioadhesive drug carriers against tuberculosis (TB), in order to reduce the drug dosage frequency of antitubercular drugs and thus improve patient compliance in TB chemotherapy.

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