Open AccessContinuous and 4 h infusion of amphotericin B: a comparative study involving high-risk haematology patients
Author(s) -
Anton Y. Peleg,
Marion L. Woods
Publication year - 2004
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkh403
Subject(s) - medicine , neutropenia , nephrotoxicity , hematology , odds ratio , confidence interval , gastroenterology , retrospective cohort study , amphotericin b , surgery , toxicity , antifungal , dermatology
To assess whether a continuous infusion of amphotericin B (CI-AmB) is less nephrotoxic than a 4 h infusion in haematology patients with fever and neutropenia, including bone-marrow transplant recipients. Efficacy was assessed as a secondary end-point.
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