Therapeutic efficacy of the magainin analogue MSI-78 in different intra-abdominal sepsis rat models
Author(s) -
Andrea Giacometti,
Roberto Ghiselli,
Oscar Cirioni,
Federico Mocchegiani,
Giuseppina D’Amato,
Fiorenza Orlando,
Valerio Sisti,
Wojciech Kamysz,
Carmela Silvestri,
Piotr Naldoski,
Jerzy Łukasiak,
Vittorio Saba,
Giorgio Scalise
Publication year - 2004
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkh390
Subject(s) - escherichia coli , antimicrobial , magainin , piperacillin , microbiology and biotechnology , sepsis , septic shock , in vivo , chemistry , pharmacology , medicine , antimicrobial peptides , biology , pseudomonas aeruginosa , biochemistry , bacteria , genetics , gene
This study was designed to investigate the antimicrobial and anti-endotoxin activity of MSI-78, a synthetic cationic peptide analogue of magainin 2.
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