Ultrastructure of Streptococcus pneumoniae after exposure to xylitol | Zendy

Terhi Tapiainen | Zendy; Raija Sormunen | Zendy; Tarja Kaijalainen | Zendy; Tero Kontiokari | Zendy; Irma Ikäheimo | Zendy; Matti Uhari | Zendy

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Ultrastructure of Streptococcus pneumoniae after exposure to xylitol

Author(s) -

Terhi Tapiainen,

Raija Sormunen,

Tarja Kaijalainen,

Tero Kontiokari,

Irma Ikäheimo,

Matti Uhari

Publication year - 2004

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkh302

Subject(s) - xylitol , streptococcus pneumoniae , microbiology and biotechnology , pneumococcal infections , otitis , haemophilus influenzae , medicine , biology , biochemistry , antibiotics , surgery , fermentation

Xylitol is a sugar alcohol which reduces the growth of Streptococcus pneumoniae and the adherence of pneumococci and Haemophilus influenzae to nasopharyngeal cells. Xylitol prevents acute otitis media but does not decrease nasopharyngeal carriage of pneumococci. We hypothesized that xylitol could affect the surface structures of viable pneumococci, which would further explain the mechanism of action of xylitol in preventing acute otitis media.

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