Open AccessIn vitro synergic antifungal effect of MUC7 12-mer with histatin-5 12-mer or miconazole
Author(s) -
Guoxian Wei
Publication year - 2004
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkh181
Subject(s) - miconazole , in vitro , antifungal , mucin , miconazole nitrate , chemistry , peptide , pharmacology , microbiology and biotechnology , biochemistry , biology
MUC7 12-mer (RKSYKCLHKRCR), a cationic peptide derived from human salivary MUC7 mucin, exhibits potent in vitro antifungal activity, as determined by killing assays in phosphate buffer. In this study we examined the MUC7 12-mer antifungal activity alone or in combination with other antifungal agents in LYM medium (modified RPMI 1640).
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