Open AccessSerum and sputum concentrations following the oral administration of linezolid in adult patients with cystic fibrosis
Author(s) -
Dinesh Saralaya
Publication year - 2004
Publication title -
the journal of antimicrobial chemotherapy/journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkh072
Subject(s) - linezolid , sputum , medicine , dosing , cystic fibrosis , antibiotics , gastroenterology , oral administration , antibacterial agent , pharmacology , staphylococcus aureus , microbiology and biotechnology , tuberculosis , pathology , bacteria , biology , vancomycin , genetics
Linezolid is a new oxazolidinone antibiotic with efficacy against a broad range of Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA). In this study, we have determined the serum and sputum linezolid concentrations in adults with cystic fibrosis (CF) following oral drug administration.