Comment on: Effect of antiretroviral protease inhibitors alone, and in combination with paromomycin, on the excystation, invasion and in vitro development of Cryptosporidium parvum

Sir, I would like to comment on the paper by Hommer et al.,1 to correct an erroneous statement in the portion of the Introduction meant to justify the need for this work. After quoting a 7-year-old study and a 6-year-old reference book, the article states quite flatly that no effective treatment for cryptosporidiosis is currently available. In fact, multiple studies,2–6 both open-label and double-blind placebocontrolled, have been published showing the efficacy of nitazoxanide, both in immune-competent and immune-suppressed populations. It has been approved and marketed, as Alinia, for several years now in Central and South America and has been approved by the US FDA for the treatment of cryptosporidiosis in children.