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In vitro effects of combinations of antipseudomonal agents against seven strains of multidrug-resistant Pseudomonas aeruginosa
Author(s) -
Shigeharu Oie
Publication year - 2003
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkg478
Subject(s) - aztreonam , ceftazidime , amikacin , microbiology and biotechnology , piperacillin , agar dilution , cefoperazone , antibiotics , sulbactam , pseudomonas aeruginosa , biology , minimum inhibitory concentration , medicine , imipenem , bacteria , antibiotic resistance , genetics
The aim of this study was to evaluate the combined effects of antibiotic combinations by agar incorporation inhibitory tests and by time-kill tests on seven geographically and epidemiologically distinct isolates of multidrug-resistant Pseudomonas aeruginosa. All seven strains were resistant to piperacillin, meropenem, ceftazidime, cefoperazone-sulbactam, aztreonam, amikacin and ciprofloxacin.

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