Open AccessInhibition of Streptococcus mutans biofilm accumulation and polysaccharide production by apigenin and tt-farnesol
Author(s) -
H. Koo
Publication year - 2003
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkg449
Subject(s) - biofilm , farnesol , apigenin , streptococcus mutans , microbiology and biotechnology , polysaccharide , chemistry , food science , biochemistry , flavonoid , biology , bacteria , genetics , antioxidant
Apigenin is a potent inhibitor of glucosyltransferases and tt-farnesol affects the membrane integrity of Streptococcus mutans. We investigated the influence of apigenin and tt-farnesol, alone and in combination, on the accumulation, polysaccharide composition and viability of S. mutans UA159 biofilms.
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