Prophylactic efficacy of linezolid alone or combined with levofloxacin and vancomycin in a rat subcutaneous pouch model of graft infection caused by Staphylococcus epidermidis with intermediate resistance to glycopeptides | Zendy

Andrea Giacometti | Zendy; Roberto Ghiselli | Zendy; Oscar Cirioni | Zendy; Federico Mocchegiani | Zendy; Fiorenza Orlando | Zendy; Maria Simona Del Prete | Zendy; Giuseppina D’Amato | Zendy; Carmela Silvestri | Zendy; Vittorio Saba | Zendy; Giorgio Scalise | Zendy

Open Access

Prophylactic efficacy of linezolid alone or combined with levofloxacin and vancomycin in a rat subcutaneous pouch model of graft infection caused by Staphylococcus epidermidis with intermediate resistance to glycopeptides

Author(s) -

Andrea Giacometti,

Roberto Ghiselli,

Oscar Cirioni,

Federico Mocchegiani,

Fiorenza Orlando,

Maria Simona Del Prete,

Giuseppina D’Amato,

Carmela Silvestri,

Vittorio Saba,

Giorgio Scalise

Publication year - 2003

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkg396

Subject(s) - linezolid , levofloxacin , staphylococcus epidermidis , vancomycin , medicine , antibiotics , methicillin resistant staphylococcus aureus , glycopeptide , staphylococcal infections , microbiology and biotechnology , surgery , staphylococcus aureus , biology , bacteria , genetics

A rat model was used to investigate the efficacy of linezolid, alone or in combination with levofloxacin and vancomycin, in the prevention of vascular prosthetic graft infection resulting from methicillin-resistant Staphylococcus epidermidis with intermediate resistance to glycopeptides.

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