Effect of protease inhibitor-containing regimens on lymphocyte multidrug resistance transporter expression | Zendy

Jennifer Lynn Ford | Zendy

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Effect of protease inhibitor-containing regimens on lymphocyte multidrug resistance transporter expression

Author(s) -

Jennifer Lynn Ford

Publication year - 2003

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkg381

Subject(s) - indinavir , nelfinavir , saquinavir , ritonavir , lopinavir , amprenavir , pharmacology , p glycoprotein , biology , protease inhibitor (pharmacology) , peripheral blood mononuclear cell , stavudine , microbiology and biotechnology , virology , protease , multiple drug resistance , viral load , in vitro , zidovudine , hiv 1 protease , drug resistance , virus , biochemistry , viral disease , antiretroviral therapy , enzyme

Increased expression of multidrug resistance transporters, such as P-glycoprotein (P-gp), has been suggested as a potential mechanism for decreased protease inhibitor (PI) availability at certain intracellular sites and tissue compartments.

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