Comparative antimicrobial activity of levofloxacin and ciprofloxacin against Streptococcus pneumoniae | Zendy

Mark W. Garrison | Zendy

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Comparative antimicrobial activity of levofloxacin and ciprofloxacin against Streptococcus pneumoniae

Author(s) -

Mark W. Garrison

Publication year - 2003

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkg380

Subject(s) - levofloxacin , ciprofloxacin , streptococcus pneumoniae , clearance , microbiology and biotechnology , ofloxacin , medicine , antibacterial agent , regimen , antimicrobial , antibiotics , pharmacology , biology , urology

Levofloxacin has good coverage against both Gram-positive and Gram-negative pathogens. Recent reports demonstrate enhanced activity associated with a higher 750 mg dosage of levofloxacin. The objective of this study was to comparatively evaluate the activity of common regimens of levofloxacin (500 mg) and ciprofloxacin (500 mg), and a higher 750 mg levofloxacin regimen against penicillin susceptible and non-susceptible strains of S. pneumoniae.

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