Antimicrobial activity of SMAP-29 against the Bacteroides fragilis group and clostridia | Zendy

Alessandra Arzese | Zendy; Barbara Skerlavaj | Zendy; Linda Tomasinsig | Zendy; Renato Gennaro | Zendy; Margherita Zanetti | Zendy

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Antimicrobial activity of SMAP-29 against the Bacteroides fragilis group and clostridia

Author(s) -

Alessandra Arzese,

Barbara Skerlavaj,

Linda Tomasinsig,

Renato Gennaro,

Margherita Zanetti

Publication year - 2003

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkg372

Subject(s) - bacteroides fragilis , microbiology and biotechnology , clostridium perfringens , biology , clostridia , clostridium , antimicrobial , anaerobic bacteria , bacteria , peptide , bacteroides , antibiotics , biochemistry , genetics

The cathelicidin-derived peptide SMAP-29 exerts rapid and broad-spectrum antimicrobial activity against aerobic bacteria and fungi. In this study, the effects of the peptide against the Bacteroides fragilis group, including antibiotic-resistant isolates, Clostridium perfringens and Clostridium difficile reference and clinical isolates, were investigated.

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