Susceptibility to rifaximin of Vibrio cholerae strains from different geographical areas | Zendy

Maria Scrascia | Zendy

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Susceptibility to rifaximin of Vibrio cholerae strains from different geographical areas

Author(s) -

Maria Scrascia

Publication year - 2003

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkg318

Subject(s) - rifaximin , vibrio cholerae , cholera , microbiology and biotechnology , antimicrobial , antibiotics , vibrionaceae , biology , bacteria , genetics

Four hundred and eight clinical strains of Vibrio cholerae isolated from different geographical areas and with different antimicrobial resistance patterns were tested for susceptibility to rifaximin, a non-absorbable antibiotic active in vitro against Gram-negative bacteria. The MICs ranged from 0.5 to 4 mg/l for all strains. These values and the pharmacokinetic properties suggest rifaximin as an attractive antimicrobial agent for cholera.

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