Liposomal tobramycin against pulmonary infections of Pseudomonas aeruginosa: a pharmacokinetic and efficacy study following single and multiple intratracheal administrations in rats
Author(s) -
JeanFrançois Marier
Publication year - 2003
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkg317
Subject(s) - tobramycin , pharmacokinetics , pseudomonas aeruginosa , pharmacology , medicine , antibacterial agent , aminoglycoside , minimum inhibitory concentration , cystic fibrosis , antibiotics , microbiology and biotechnology , chemistry , biology , bacteria , genetics
To determine the pharmacokinetics and efficacy of tobramycin against pulmonary infections of Pseudomonas aeruginosa in rats after intratracheal administration of conventional and liposomal formulations.
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