Macrolide resistance determinants of group A streptococci in Ankara, Turkey | Zendy

Ziya Cibali Açıkgöz | Zendy

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Macrolide resistance determinants of group A streptococci in Ankara, Turkey

Author(s) -

Ziya Cibali Açıkgöz

Publication year - 2003

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkg300

Subject(s) - erythromycin , spiramycin , clindamycin , microbiology and biotechnology , biology , antibiotics , macrolide antibiotics , antibiotic resistance , lincosamides , tetracycline

Macrolide-lincosamide-streptogramin B (MLSB) resistance determinants of group A streptococci (GAS) in Ankara, Turkey, were defined for the first time. ISOLATES AND METHODS: A total of 1355 GAS isolates, collected from three different regions of Ankara, were screened for erythromycin resistance. Resistance phenotypes were determined by a triple-disc test, and the gene determinants responsible were determined by PCR. MICs of erythromycin, clindamycin and spiramycin were measured for the resistant isolates, and susceptibility rates to some further antibiotics were determined.

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