Evaluation of fusidic acid in therapy of experimental Staphylococcus aureus meningitis
Author(s) -
Christian Østergaard
Publication year - 2003
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkg231
Subject(s) - fusidic acid , staphylococcus aureus , medicine , antibiotics , meningitis , staphylococcal infections , microbiology and biotechnology , pharmacokinetics , antimicrobial , micrococcaceae , pharmacology , antibacterial agent , gastroenterology , surgery , biology , bacteria , genetics
Combination therapy that includes fusidic acid, an antimicrobial agent highly active against staphylococci, has been recommended in the treatment of patients with Staphylococcus aureus meningitis. The aim of this study was to evaluate the pharmacokinetic, CSF bactericidal and anti-inflammatory properties of fusidic acid.
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