Florfenicol resistance in Salmonella enterica serovar Newport mediated by a plasmid related to R55 from Klebsiella pneumoniae | Zendy

Dominique Meunier | Zendy; Sylvie Baucheron | Zendy; E. Chaslus-Dancla | Zendy; J.L. Martel | Zendy; Axel Cloeckaert | Zendy

Open Access

Florfenicol resistance in Salmonella enterica serovar Newport mediated by a plasmid related to R55 from Klebsiella pneumoniae

Author(s) -

Dominique Meunier,

Sylvie Baucheron,

E. Chaslus-Dancla,

J.L. Martel,

Axel Cloeckaert

Publication year - 2003

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkg141

Subject(s) - microbiology and biotechnology , klebsiella pneumoniae , salmonella enterica , serotype , plasmid , salmonella , biology , enterobacteriaceae , klebsiella , klebsiella oxytoca , virology , bacteria , escherichia coli , gene , biochemistry , genetics

Florfenicol resistance has emerged over the past few years in multidrug-resistant Salmonella enterica serovars Typhimurium, Agona and Paratyphi B. The floR gene encoding florfenicol resistance is chromosomally located in these serovars within a genomic island of 43 kb called SGI1 (Salmonella genomic island 1). In the present study, we characterized florfenicol resistance in a strain of S. enterica serovar Newport isolated from a turkey in 1990 and that lacked SGI1. Florfenicol resistance was mediated by a conjugative plasmid related to R55 from Klebsiella pneumoniae, which was characterized initially in the 1970s and harbours a gene 95% identical to floR.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research