Optimizing ceftazidime pharmacodynamics in patients with acute exacerbation of severe chronic bronchitis | Zendy

Annette Lubasch | Zendy

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Optimizing ceftazidime pharmacodynamics in patients with acute exacerbation of severe chronic bronchitis

Author(s) -

Annette Lubasch

Publication year - 2003

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkg111

Subject(s) - chronic bronchitis , ceftazidime , medicine , pharmacodynamics , exacerbation , bronchitis , pharmacokinetics , gastroenterology , biology , bacteria , pseudomonas aeruginosa , genetics

Implementation of current pharmacodynamic knowledge could enhance clinical results, avoid resistance development and reduce treatment costs. In this open, randomized, multicentre study, we evaluated the clinical and bacteriological outcome and pharmacokinetic as well as pharmacodynamic parameters of two ceftazidime therapy regimens in patients with acute exacerbation of severe chronic bronchitis (AECB).

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