Inhibitory effect of roxithromycin on the local levels of bone-resorbing cytokines in an experimental model of murine osteomyelitis | Zendy

Takashi Yoshii | Zendy; Shinya Magara | Zendy; Daisuke Miyai | Zendy; Eiji Kuroki | Zendy; Hidetaka Nishimura | Zendy; Shungo Furudoi | Zendy; Takahide Komori | Zendy

Open Access

Inhibitory effect of roxithromycin on the local levels of bone-resorbing cytokines in an experimental model of murine osteomyelitis

Author(s) -

Takashi Yoshii,

Shinya Magara,

Daisuke Miyai,

Eiji Kuroki,

Hidetaka Nishimura,

Shungo Furudoi,

Takahide Komori

Publication year - 2002

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkf124

Subject(s) - roxithromycin , osteomyelitis , staphylococcus aureus , medicine , cytokine , tumor necrosis factor alpha , interleukin 6 , alpha (finance) , immunology , pharmacology , microbiology and biotechnology , antibiotics , surgery , biology , bacteria , genetics , erythromycin , construct validity , patient satisfaction

The purpose of this study was to evaluate the inhibitory effect of roxithromycin on the production of interleukin (IL)-1beta, IL-6 and tumour necrosis factor-alpha (TNF-alpha) in a murine tibial osteomyelitis model using Staphylococcus aureus.

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