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Conventional culture-based phenotypic and genomic surveillance has drawbacks and may not necessarily reflect the true burden of antibiotic resistance. The integration of metagenomic surveillance with transcriptomics and proteomics will yield a step change in the utility of surveillance data from treatment options to precision medicine.

BSAC Vanguard Series: From treatment options to precision medicine: the future of ‘omics-based’ antibiotic resistance surveillance data