Open AccessPyocin efficacy in a murine model of Pseudomonas aeruginosa sepsis
Author(s) -
Anne Six,
Khédidja Mosbahi,
Madhuri Barge,
Colin Kleanthous,
Thomas J. Evans,
Daniel Walker
Publication year - 2021
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkab199
Subject(s) - pseudomonas aeruginosa , sepsis , galleria mellonella , antibiotics , microbiology and biotechnology , in vivo , medicine , antimicrobial , biology , immunology , bacteria , virulence , gene , biochemistry , genetics
Bloodstream infections with antibiotic-resistant Pseudomonas aeruginosa are common and increasingly difficult to treat. Pyocins are naturally occurring protein antibiotics produced by P. aeruginosa that have potential for human use.
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