Optical maps of plasmids as a proxy for clonal spread of MDR bacteria: a case study of an outbreak in a rural Ethiopian hospital | Zendy

Yii-Lih Lin | Zendy; Tsegaye Sewunet | Zendy; Sriram KK | Zendy; Christian G. Giske | Zendy; Fredrik Westerlund | Zendy

Open Access

Optical maps of plasmids as a proxy for clonal spread of MDR bacteria: a case study of an outbreak in a rural Ethiopian hospital

Author(s) -

Yii-Lih Lin,

Tsegaye Sewunet,

Sriram KK,

Christian G. Giske,

Fredrik Westerlund

Publication year - 2020

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkaa258

Subject(s) - plasmid , biology , bacteria , antibiotic resistance , multilocus sequence typing , escherichia coli , gene , typing , genome , outbreak , microbiology and biotechnology , horizontal gene transfer , genetics , virology , genotype

MDR bacteria have become a prevailing health threat worldwide. We here aimed to use optical DNA mapping (ODM) as a rapid method to trace nosocomial spread of bacterial clones and gene elements. We believe that this method has the potential to be a tool of pivotal importance for MDR control.

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