Open AccessIn vitro dynamics and mechanisms of resistance development to imipenem and imipenem/relebactam in Pseudomonas aeruginosa
Author(s) -
María A. Gomis-Font,
Gabriel Cabot,
Irina Sánchez-Diener,
Pablo A. Fraile-Ribot,
Carlos Juan,
Bartolomé Moyá,
Laura Zamorano,
Antonio Oliver
Publication year - 2020
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkaa206
Subject(s) - pseudomonas aeruginosa , imipenem , microbiology and biotechnology , in vitro , biology , antibiotic resistance , antibiotics , bacteria , genetics
We analysed the dynamics and mechanisms of resistance development to imipenem alone or combined with relebactam in Pseudomonas aeruginosa WT (PAO1) and mutator (PAOMS; ΔmutS) strains.
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