In vitro activity of telithromycin against Streptococcus pneumoniae resistant to other antibiotics, including cefotaxime | Zendy

Peter Fuchs | Zendy

Open Access

In vitro activity of telithromycin against Streptococcus pneumoniae resistant to other antibiotics, including cefotaxime

Author(s) -

Peter Fuchs

Publication year - 2002

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/49.2.399

Subject(s) - telithromycin , cefotaxime , streptococcus pneumoniae , microbiology and biotechnology , antibiotics , ketolide , trimethoprim , antibacterial agent , sulfamethoxazole , streptococcaceae , pneumococcal infections , biology , virology

A total of 407 isolates of Streptococcus pneumoniae, most of which were resistant to one or more antibiotics, were tested for susceptibility to telithromycin and four other agents. Telithromycin was the most active agent tested, with 98% of isolates susceptible to < or = 1.0 mg/L. For strains resistant to the other antibiotics, susceptibility to telithromycin ranged from 98.6% for strains resistant to trimethoprim/sulfamethoxazole to 94.4% for strains resistant to cefotaxime.

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