The fate of antibiotic resistance marker genes in transgenic plant feed material fed to chickens
Author(s) -
Philip Chambers
Publication year - 2002
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/49.1.161
Subject(s) - biology , transgene , gene , marker gene , genetically modified crops , antibiotic resistance , ampicillin , antibiotics , bacteria , amp resistance , microbiology and biotechnology , botany , genetics
We have examined the fate of an antibiotic resistance marker, incorporated into transgenic maize when fed to chicks. Plant-derived markers were found in the crops of five birds fed transgenic maize and in the stomach contents of two birds. The plant-derived marker gene was not found in the intestines. The survival of the antibiotic resistance marker gene mirrored that of plant DNA targets, demonstrating that it survives no better than other DNA and indicating that it is very unlikely that bacteria in the gut of chickens will be transformed to ampicillin resistance when the birds are fed transgenic maize.
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