Features and trends in Helicobacter pylori antibiotic resistance in Lisbon area, Portugal (1990-1999) | Zendy

José Cabrita | Zendy

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Features and trends in Helicobacter pylori antibiotic resistance in Lisbon area, Portugal (1990-1999)

Author(s) -

José Cabrita

Publication year - 2000

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/46.6.1029

Subject(s) - ciprofloxacin , metronidazole , clarithromycin , helicobacter pylori , amoxicillin , tetracycline , antibiotics , medicine , antibacterial agent , antibiotic resistance , microbiology and biotechnology , population , incidence (geometry) , gastroenterology , biology , environmental health , physics , optics

The features of Helicobacter pylori antibiotic resistance in Lisbon from 1990 to 1999 were studied. Overall resistance rates to amoxycillin, tetracycline, metronidazole, clarithromycin and ciprofloxacin were 0, 0, 30.6, 19.0 and 9.6%, respectively. The incidence of resistance to clarithromycin was much higher in isolates from children (44.8%) than adults (14.6%). For metronidazole, the contrary was observed (children: 19.0%, adults: 32.3%). Ciprofloxacin-resistant isolates were all from adult patients. Concerning the adult population, the resistance rate to metronidazole showed a slight increase during the decade, while for clarithromycin and ciprofloxacin a significant increase was observed (4.6 to 22.0% and 0 to 20.9%, respectively).

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