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Susceptibility testing of Haemophilus influenzae to clarithromycin
Author(s) -
R. Paton,
Jorge Arnold,
J. Cockburn,
F.X.S. Emmanuel
Publication year - 2000
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/45.4.529
Subject(s) - haemophilus influenzae , clarithromycin , microbiology and biotechnology , macrolide antibiotics , antibacterial agent , antibiotics , medicine , biology , erythromycin
Susceptibility testing of Haemophilus influenzae to the macrolide compounds has often been problematic. This is as a result of the inability of many isolates of H. influenzae to grow without the addition of 5% CO2 to the incubation atmosphere and the subsequent detrimental effect that CO2 has on the activity of the macrolide group of compounds. This report describes refinements and recommendations for susceptibility testing of H. influenzae to the macrolide clarithromycin.

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