In-vitro activity of antibiotics against Legionella pneumophila isolates from water systems | Zendy

Athanassios Tsakris | Zendy; S. AlexiouDaniel | Zendy; Efimia Souliou | Zendy; A. Antoniadis | Zendy

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In-vitro activity of antibiotics against Legionella pneumophila isolates from water systems

Author(s) -

Athanassios Tsakris,

S. AlexiouDaniel,

Efimia Souliou,

A. Antoniadis

Publication year - 1999

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/44.5.693

Subject(s) - legionella pneumophila , pefloxacin , microbiology and biotechnology , legionella , ciprofloxacin , antibiotics , erythromycin , legionnaires' disease , rifampicin , clarithromycin , antibacterial agent , biology , bacteria , ofloxacin , genetics

The activity of five antibiotics was tested against 82 isolates of Legionella pneumophila obtained from water systems in nine European countries. All isolates were susceptible to clarithromycin (MICs 0. 03-0.5 mg/L), erythromycin (MICs 0.125-2.0 mg/L), ciprofloxacin (MICs 0.06-0.25 mg/L), pefloxacin (MICs 0.06-0.5 mg/L) and rifampicin (MICs < or = 0.007-0.015 mg/L). It seems that antibiotics used for legionellosis continue to exhibit good activity against L. pneumophila isolates from environmental sources in European countries.

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