Resistance to methicillin in isolates of Staphylococcus aureus from blood and cerebrospinal fluid in Wales, 1993–1997 | Zendy

Mari Morgan | Zendy; R Salmon | Zendy; D. Evans-Williams | Zendy; I.K. Hosein | Zendy; D.N. Looker | Zendy

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Resistance to methicillin in isolates of Staphylococcus aureus from blood and cerebrospinal fluid in Wales, 1993–1997

Author(s) -

Mari Morgan,

R Salmon,

D. Evans-Williams,

I.K. Hosein,

D.N. Looker

Publication year - 1999

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/44.4.541

Subject(s) - staphylococcus aureus , sepsis , cerebrospinal fluid , microbiology and biotechnology , blood culture , micrococcaceae , medicine , methicillin resistant staphylococcus aureus , staphylococcus , staphylococcal infections , meticillin , biology , antibiotics , immunology , bacteria , antibacterial agent , genetics

Surveillance data for organisms isolated from blood cultures and cerebrospinal fluid (CSF) specimens has been gathered electronically in Wales since 1993. Over this period the proportion of total reported organisms from blood cultures and CSF represented by methicillin-resistant staphylococci (MRSA) has risen steadily. This has corresponded to a rise in rates of methicillin resistance amongst Staphylococcus aureus isolated from blood cultures and CSF from 4 to 43%. In certain age/gender groups in 1997, more than 50% of isolates of S. aureus were resistant to methicillin, suggesting that a change in empirical treatment may be necessary for suspected staphylococcal sepsis.

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