Antimicrobial resistance patterns in urinary isolates from nursing home residents. Fifteen years of data reviewed
Author(s) -
M. Vromen,
A. J. A. M. van der Ven,
A. Knols,
M. E. E. Stobberingh
Publication year - 1999
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/44.1.113
Subject(s) - nitrofurantoin , norfloxacin , microbiology and biotechnology , proteus , medicine , urinary system , antibiotics , antibiotic resistance , nursing homes , antimicrobial , escherichia coli , nursing , biology , ciprofloxacin , biochemistry , gene
The antibiotic resistance patterns of gram-negative bacteria isolated from nursing home patients between 1983 and 1997 were analysed. Escherichia coli was the most prevalent isolate (48%) followed by Proteus spp. (26%) and other Enterobacteriaceae (20%). During the study period, the susceptibility of E. coli decreased for co-trimoxazole (79% to 62%), increased for nitrofurantoin (79% to 91%) and remained unchanged for amoxycillin (41%). Susceptibility to norfloxacin, available from 1990, decreased from 87% to 71%. Similar trends were observed when the susceptibilities of all gram-negative urinary pathogens were combined. The changes in susceptibility can probably be attributed to the empirical prescribing practices in the nursing homes studied.
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