Bioassays for itraconazole blood levels: an interlaboratory collaborative study | Zendy

Frank C. Odds | Zendy; B. Dupont | Zendy; Michael G. Rinaldi | Zendy; David A. Stevens | Zendy; David W. Warnock | Zendy; Robert Woestenborghs | Zendy

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Bioassays for itraconazole blood levels: an interlaboratory collaborative study

Author(s) -

Frank C. Odds,

B. Dupont,

Michael G. Rinaldi,

David A. Stevens,

David W. Warnock,

Robert Woestenborghs

Publication year - 1999

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/43.5.723

Subject(s) - itraconazole , bioassay , antifungal , pharmacology , biology , microbiology and biotechnology , genetics

Duplicate bioassays for itraconazole and hydroxy-itraconazole were run with 30 serum samples in five laboratories, each using a different method. Both itraconazole and hydroxy-itraconazole were used as standards. Despite quantitative variations, the results of the bioassays correlated sufficiently to indicate the relative level of antifungal activity in the test samples.

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