Failure of Neisseria gonorrhoeae to grow in the ATB NH susceptibility test system | Zendy

H Young | Zendy; A Moyes | Zendy; C. Hardie | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Failure of Neisseria gonorrhoeae to grow in the ATB NH susceptibility test system

Author(s) -

H Young,

A Moyes,

C. Hardie

Publication year - 1997

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/40.4.579

Subject(s) - neisseria gonorrhoeae , microbiology and biotechnology , neisseria meningitidis , haemophilus influenzae , serotype , neisseria , biology , antibiotics , neisseriaceae , medicine , bacteria , genetics

The ATB NH system designed for antibiotic susceptibility testing of Neisseria gonorrhoeae, Neisseria meningitidis and Haemophilus influenzae was evaluated using 94 clinical isolates of gonococci representing a wide variety of serovar/auxotype strains. Using the manufacturer's automated system 55% of the clinical isolates failed to grow, compared with a 33% failure rate for manual processing and visual reading. Growth failure was significantly higher with 1A isolates (73% automated and 69% manual) than with 1B isolates (49% automated and 25% manual). The higher failure rate of 1A isolates correlated with multiple auxotrophy. The inability of the ATB NH system to support the growth of common serovar/auxotypes makes the ATB NH system unsuitable for antibiotic susceptibility testing of N. gonorrhoeae.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research