Novel transferable beta-lactam resistance with cephalosporinase characteristics in Salmonella enteritidis | Zendy

Olivier Gaillot | Zendy

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Novel transferable beta-lactam resistance with cephalosporinase characteristics in Salmonella enteritidis

Author(s) -

Olivier Gaillot

Publication year - 1997

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/39.1.85

Subject(s) - salmonella enteritidis , cephalosporin , microbiology and biotechnology , salmonella , plasmid , biology , enterobacteriaceae , beta lactamase , bacteria , escherichia coli , genetics , antibiotics , gene

An isolate of Salmonella enteritidis was found to produce a plasmid-encoded beta-lactamase (DHA-1) that conferred resistance to extended-spectrum cephalosporins and cephamycins. The substrate and inhibition profiles of this enzyme resemble a class C beta-lactamase. This is the first report of a plasmid-mediated cephalosporinase of this class in the Salmonella genus.

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