In-vitro activity of chlorhexidine, hexetidine and bacitracin against perinatal pathogens | Zendy

Albert H. Adriaanse | Zendy; Harry L. Muytjens | Zendy; F W Heessen | Zendy; J.M.D. Galama | Zendy; J. A. A. HoogkampKorstanje | Zendy

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In-vitro activity of chlorhexidine, hexetidine and bacitracin against perinatal pathogens

Author(s) -

Albert H. Adriaanse,

Harry L. Muytjens,

F W Heessen,

J.M.D. Galama,

J. A. A. HoogkampKorstanje

Publication year - 1996

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/37.1.192

Subject(s) - bacitracin , chlorhexidine , microbiology and biotechnology , in vitro , anti infective agents , medicine , biology , chemistry , antibiotics , antimicrobial , dentistry , biochemistry

Sir, To prevent microbial contamination and subsequent infection of the newborn during birth, it would be desirable to have a safe and efficacious antimicrobial agent that could be applied to the vaginal mucosa to prevent transmission of neonatal pathogens during labour. We studied the in-vitro activities of three possibly useful agents: chlorhexidine, hexetidine and bacitracin against clinical isolates of Chlamydia trachomatis (5 strains), Ureaplasma urealyticum (4), Mycoplasma hominis (4), Streptococcus agalactiae (50), Escherichia coli (50) and Listeria monocytogenes (10). Reference strains were C. trachomatis ATCC VR348B, U. urealyticum ATCC 27618 and ATCC 27813, M. hominis ATCC 14027 and ATCC 23114, S. agalactiae ATCC 13813 and NTCC 8181, E. coli ATCC 25922 and Staphylococcus aureus ATCC 29213.

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