Interleukin 21 Reinvigorates the Antiviral Activity of Hepatitis B Virus (HBV)–Specific CD8+ T Cells in Chronic HBV Infection | Zendy

Libo Tang | Zendy; Chengcong Chen | Zendy; Xueping Gao | Zendy; Wanyue Zhang | Zendy; Xin Yan | Zendy; Yang Zhou | Zendy; Ling Guo | Zendy; Xinchun Zheng | Zendy; Weibin Wang | Zendy; Fuqiang Yang | Zendy; Guangze Liu | Zendy; Jian Sun | Zendy; Jinlin Hou | Zendy; Yongyin Li | Zendy

Open Access

Interleukin 21 Reinvigorates the Antiviral Activity of Hepatitis B Virus (HBV)–Specific CD8+ T Cells in Chronic HBV Infection

Author(s) -

Libo Tang,

Chengcong Chen,

Xueping Gao,

Wanyue Zhang,

Xin Yan,

Yang Zhou,

Ling Guo,

Xinchun Zheng,

Weibin Wang,

Fuqiang Yang,

Guangze Liu,

Jian Sun,

Jinlin Hou,

Yongyin Li

Publication year - 2018

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1093/infdis/jiy576

Subject(s) - virology , hepatitis b virus , virus , medicine , immunology , cd8 , biology , immune system

Strategies that target functional recovery of exhausted hepatitis B virus (HBV)-specific CD8+ T cells are beneficial for viral control, but the potential for interleukin 21 (IL-21) to rescue CD8+ T-cell function is not well understood.

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