Macrophage Activation Marker Soluble CD163 Is a Dynamic Marker of Liver Fibrogenesis in Human Immunodeficiency Virus/Hepatitis C Virus Coinfection | Zendy

Anna Lidofsky | Zendy; Jacinta A. Holmes | Zendy; Eoin R. Feeney | Zendy; Annie J. Kruger | Zendy; Shadi Salloum | Zendy; Hui Zheng | Zendy; Isabel S Seguin | Zendy; Akif Altınbaş | Zendy; Ricard Masia | Zendy; Kathleen E. Corey | Zendy; Jenna Gustafson | Zendy; Esperance Schaefer | Zendy; Peter W. Hunt | Zendy; Steven G. Deeks | Zendy; Ma Somsouk | Zendy; Kara W. Chew | Zendy; Raymond T. Chung | Zendy; Nadia Alatrakchi | Zendy

Open Access

Macrophage Activation Marker Soluble CD163 Is a Dynamic Marker of Liver Fibrogenesis in Human Immunodeficiency Virus/Hepatitis C Virus Coinfection

Author(s) -

Anna Lidofsky,

Jacinta A. Holmes,

Eoin R. Feeney,

Annie J. Kruger,

Shadi Salloum,

Hui Zheng,

Isabel S Seguin,

Akif Altınbaş,

Ricard Masia,

Kathleen E. Corey,

Jenna Gustafson,

Esperance Schaefer,

Peter W. Hunt,

Steven G. Deeks,

Ma Somsouk,

Kara W. Chew,

Raymond T. Chung,

Nadia Alatrakchi

Publication year - 2018

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1093/infdis/jiy331

Subject(s) - coinfection , virology , hepatitis c virus , virus , immunology , biology , medicine

Coinfection with human immunodeficiency virus (HIV) accelerates hepatitis C virus (HCV)-related liver fibrosis. Macrophages are triggered during both viral infections and are critical in liver inflammation/fibrogenesis. Liver fibrosis strongly associates with serum soluble CD163 (sCD163, a macrophage activation marker); comprehensive evaluation in HIV/HCV coinfection is lacking.

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